EN 17681-1 EUROPEANSTANDARD NORME EUROPEENNE EUROPAISCHE NORM April 2025 ICS59.080.01 Supersedes EN 17681-1:2022 English Version Textiles and textile products - Per- and polyfluoroalkyl substances (PFAS) - Part 1: Analysis of an alkaline extract using liquid chromatography and tandem mass spectrometry Textiles et produits textiles - Substances Textilien und textile Erzeugnisse - Per- und perfluoroalkylees et polyfluoroalkylées (PFAS) - Partie polyfluorierte Alkylverbindungen (PFAS) - Teil 1: 1 : Analyse d'un extrait alcalin par chromatographie en Untersuchung eines alkalischen Extraktes mittels phaseliquideetspectrométriedemasseentandem Flussigkeitschromatographieund Tandem- Massenspektrometrie This European Standard was approved by CEN on 14 March 2025. CEN members are bound to comply with the CEN/CENELEC Internal Regulations which stipulate the conditions for giving this European Standard the status of a national standard without any alteration. Up-to-date lists and bibliographical references member. This European Standard exists in three official versions (English, French, German). A version in any other language made by Centrehasthe samestatusastheofficial versions. CEN members are the national standards bodies of Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Republic of North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Tiurkiye and United Kingdom. EUROPEANCOMMITTEE FOR STANDARDIZATION COMITEEUROPEENDENORMALISATION EUROPAISCHESKOMITEEFURNORMUNG CEN-CENELECManagementCentre:RuedelaScience23,B-1040Brussels @2025CEN All rightsofexploitationinanyformandbyanymeansreserved Ref. No.EN 17681-1:2025 E worldwidefor CENnational Members. EN 17681-1:2025 (E) Contents Page European foreword. 3 Introduction ..5 1 Scope. 2 Normative references 14 3 Terms and definitions. .14 4 Principle 15 5 Reagents 15 6 Apparatus .16 7 Sampling.. 7.1 16 7.2 Sampling based on area ... 16 7.3 Sampling based on mas... 8 Procedure... 8.1 Preparation of stock solutions .... 17 8.2 Preparation of the check solution for recovery rate... 17 8.3 Preparation of calibration solutions... 17 8.4 Extraction and alkaline hydrolysis... 8.5 Analysis..... .18 9 Expression of results... 19 9.1 Calibration.... 19 9.2 Calculation of the results of individual PFAS .. .19 9.3 Calculation of the sums of certain PFAS.... 20 9.4 Limitsofquantitationofthetestmethod. 20 9.5 Reliability of the test method .. .20 10 Test report 20 Annex A (normative) Usable ions and limits of quantification for PFAS analysis of sample matrix by LC-MS/MS.... ..21 Annex B (informative) Interferences with LC-MS/MS... .24 Annex C (informative) Instrumental conditions. ...25 Annex D (informative) Reliability of the test method. AnnexE(informative)Extractionwithmethanoi.. ..30 Annex F (informative) Analysis with GC-MSD .31 Bibliography... 2 EN 17681-1:2025 (E) European foreword This document (EN 17681-1:2025) has been prepared by Technical Committee CEN/TC 248 “Textiles and textile products", the secretariat of which is held by BSI. This European Standard shall be given the status of a national standard, either by publication of an identical text or by endorsement, at the latest by October 2025, and conflicting national standards shall be withdrawn at the latest by 0ctober 2025. Attention is drawn to the possibility that some of the elements of this document may be the subject of patent rights. CEN shall not be held responsible for identifying any or all such patent rights. This document supersedes EN 17681-1:2022. This document includes the following significant technical changes with respect to EN 17681-1:2022: the title has been changed; - the introduction has been amended; -Table 1 has been revised; Table 2 has been reordered and updated with regard to new EU regulations; the majority of the sub