论文标题
基于E Coli Nissle 1917的磁控载体
Magnetically controlled vector based on E coli Nissle 1917
论文作者
论文摘要
在本文中，首先发现ECN具有天然的磁体控制特性，即E Coli Nissle 1917细胞在无人工磁标记的永久磁体的梯度磁场中移动。本文还表明，与在标准条件下的培养相比，ECN在富含铁螯合物的培养基中的培养和外部磁场的影响增加了几倍。因此，在实验室磁铁的梯度磁场中，E Coli Nissle 1917细胞的运动速度的速度达到了几个mm/s的顺序。还首次证明了E Coli Nissle 1917生物量在外部磁场中的培养加速，而培养基中铁螯合物浓度的变化对E Coli Nissle 1917培养的培养动力学没有影响。
In this paper, it is first discovered that EcN has natural magnetically controlled properties, that is, E coli Nissle 1917 cells move in a gradient magnetic field of permanent magnets without artificial magnetic labeling. It is also shown in the paper that the cultivation of EcN in a medium enriched with iron chelates and under the influence of an external magnetic field increases several times the magnetophoretic mobility of E coli Nissle 1917 cells compared to cultivation under standard conditions. Thus, the speed of movement of E coli Nissle 1917 cells in a gradient magnetic field of laboratory magnets is achieved of the order of several mm/s. It has also been shown for the first time that the cultivation of E coli Nissle 1917 biomass is accelerated by cultivation in an external magnetic field, while the change in the concentration of iron chelates in the medium has no effect on the cultivation dynamics of the E coli Nissle 1917 culture.
