论文标题
随机闪烁棘轮的运动性和能量学
Motility and Energetics of Randomly Flashing Ratchets
论文作者
论文摘要
我们考虑一个随机闪烁的棘轮，可以随机切换潜在的作用。使用耦合的Fokker-Planck方程，我们制定了测量动力学和热力学的数量表达式。扩展的数值计算列出了潜在的景观和过渡如何影响运动性和能量学。运动蛋白，动力素和动力蛋白的负载依赖性速度和能量效率进一步体现了随机闪烁的棘轮模型。我们还用两个转移的锯齿电位讨论了该系统。
We consider a randomly flashing ratchet, where the potential acting can be switched to another at random. Using coupled Fokker-Planck equations, we formulate the expressions of quantities measuring dynamics and thermodynamics. Extended numerical calculations present how the potential landscapes and the transitions affect the motility and energetics. Load-dependent velocity and energetic efficiency of motor proteins, kinesin and dynein, further exemplify the randomly flashing ratchet model. We also discuss the system with two shifted sawtooth potentials.
