论文标题
高度变形囊泡的双模式松弛
Double-mode relaxation of highly deformed vesicles
论文作者
论文摘要
已知脂质囊泡会发生复杂的构象转变，但是系统地表征非平衡膜形状动力学仍然具有挑战性。在这里，我们报告了使用Stokes陷阱从高度变形的形状中直接观察脂质囊泡松弛。囊泡形状松弛由两个不同的特征时间尺度描述，由弯曲模量和膜张力控制。有趣的是，实验结果与变形膜的粘弹性模型一致。总体而言，这些结果表明，囊泡松弛受膜弹性模量，表面张力和囊泡放气之间的相互作用。
Lipid vesicles are known to undergo complex conformational transitions, but it remains challenging to systematically characterize non-equilibrium membrane shape dynamics. Here, we report the direct observation of lipid vesicle relaxation from highly deformed shapes using a Stokes trap. Vesicle shape relaxation is described by two distinct characteristic time scales governed by the bending modulus and membrane tension. Interestingly, experimental results are consistent with a viscoelastic model of a deformed membrane. Overall, these results show that vesicle relaxation is governed by an interplay between membrane elastic moduli, surface tension, and vesicle deflation.
