论文标题
使用量子旋转链的工具研究病毒种群
Studying viral populations with tools from quantum spin chains
论文作者
论文摘要
我们研究了特征的准物种模型,其特征是序列以指定的适应度复制并在单个位点独立进行突变。然后,人口载体随时间的演变与假想时间的量子旋转密切相关。我们采用从相互作用的量子系统那里采用多种观点和工具来检查逼真的病毒群体的生长和崩溃,特别是某些HIV蛋白。所有使用的方法,包括最简单的扰动理论,都会产生一致的结果。
We study Eigen's model of quasi-species, characterized by sequences that replicate with a specified fitness and mutate independently at single sites. The evolution of the population vector in time is then closely related to that of quantum spins in imaginary time. We employ multiple perspectives and tools from interacting quantum systems to examine growth and collapse of realistic viral populations, specifically certain HIV proteins. All approaches used, including the simplest perturbation theory, give consistent results.