论文标题

构成用于检测HDR CT下颌图像中恶性病变的算法

Companding algorithm for the detection of malignant lesions in HDR CT mandibular images

论文作者

Tamir, Yuval, Spitzer, Hedva, Yarom, Noam, Barkan, Yuval, Barenboim, Silvina Friedlander, Dobriyan, Alex

论文摘要

压缩和扩展(限制)HDR计算机断层扫描(CT)图像到单个LDR图像仍然是一个相关的挑战。除了为诊断目的简化窗户设置方法的一般需求外,在下颌骨中切除恶性病变的特定临床需求,例如,软组织和骨骼中可能存在病变。成功的医学算法必须考虑到不同人体组织提出的同一特定灰度范围的要求。作为解决方案,我们提出了一种自适应多尺度对比度(AMCC)算法,该算法是通过将软阈值分离到两个通道(骨和软组织)实现的。这种分离取决于最适合牙齿的特定分辨率中的HU强度值(已在算法中计算出来的)。每个通道都包含不同的参数集。 AMCC算法成功地构成了各种各样的下颌CT HDR图像以及自然图像。两名通过“单一演示”方法评估肿瘤边界的合作医师报告说,算法输出图像的92%至少与窗口方法中的算法一样有用,而50%的算法输出图像则更好。当每个切片同时通过窗口设置方法(骨和软组织)和算法输出图像评估时,评估的93%宣布偏爱算法的输出图像。我们在这里描述了一种低成本方法,可通过提供最佳的边界定义来促进HDR图像的能力促进下颌病变的切除。

Compressing and expanding (companding) HDR computerized tomography (CT) images to a single LDR image is still a relevant challenge. Besides the general need for simplification of the window setting method for the purpose of diagnosis, there are specific clinical needs for the resection of malignant lesions in the mandible, for example, where the lesions may exist in both the soft tissue and the bone. A successful medical algorithm has to take into account the requirement to variously expose the same range of specific gray levels, when they are presented by different body tissues. As a solution, we propose an adaptive multi-scale contrast companding (AMCC) algorithm that is implemented by using soft threshold separation to two channels (bone and soft tissue). This separation is determined by the HU intensity values (that are already computed in the algorithm) in the specific resolution that is best fitted to the teeth. Each channel contains different set of parameters. The AMCC algorithm successfully and adaptively compands a large variety of mandibular CT HDR images as well as natural images. Two collaborating physicians who evaluated tumor boundaries, by the 'single presentation' method, reported that 92% of the algorithm output images were at least as useful for diagnosis as those in the window method, while 50% of the algorithm output images were better. When each slice was evaluated simultaneously, by the window setting method (bone and soft tissue) and algorithm output images, 93% of the evaluations declared a preference for the output images of the algorithm. We describe here a low-cost method for companding the HDR images with the ability to facilitate resections of mandibular lesions by providing optimal boundary definition.

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