论文标题
积极性的变化以增强流行期试样的测试
Variation of positiveness to enhance testing of specimens during an epidemic
论文作者
论文摘要
在流行病期间（例如当前的冠状病毒爆发）对怀疑患有疾病的患者的适当标本进行快速测试对于疾病的管理和控制非常重要。我们提出了一种增强加工大量收集样品的方法。该方法基于在特定构型中测试管中的混合样品，而不是测试每个管中的单个样品，并考虑受感染患者的天然病毒量因测试管中的阳性变化而产生的天然病毒量。为了说明建议方法的效率，我们在各种测试下对实际情况进行数值测试。应用所提出的方法通过大小的顺序增强了测试的数量，在没有虚假负面的情况下，所有阳性都可以识别出所有阳性，即使测试中的不确定性相对较高，也可以大大减少有效的测试时间。
Rapid testing of appropriate specimens from patients suspected for a disease during an epidemic, such as the current Coronavirus outbreak, is of a great importance for the disease management and control. We propose a method to enhance processing large amounts of collected samples. The method is based on mixing samples in testing tubes in a specific configuration, as opposed to testing single samples in each tube, and accounting for natural virus amounts in infected patients from variation of positiveness in test tubes. To illustrate the efficiency of the suggested method we carry out numerical tests for actual scenarios under various tests. Applying the proposed method enhances the number of tests by order of magnitudes, where all positives are identified with no false negatives, and the effective testing time can be reduced drastically even when the uncertainty in the test is relatively high.
