论文标题

协变量分布的能源平衡

Energy Balancing of Covariate Distributions

论文作者

Huling, Jared D., Mak, Simon

论文摘要

因果比较的偏见与治疗组之间的协变量的分布不平衡直接对应。加权策略,例如反相反得分加权尝试通过建模治疗分配机制或平衡指定的协变量力矩来减轻偏差。本文介绍了一种称为能量平衡的新加权方法,该方法旨在平衡加权协变量分布。通过直接靶向分布不平衡,可以在各种因果分析中灵活地使用提出的加权策略,包括估计平均治疗效果和个性化的治疗规则。我们的能源平衡权重(EBW)方法比现有的加权技术具有多个优势。首先,它提供了一种无需模型和强大的方法来获得不需要调整参数的协变量平衡,从而避免了对次要性质的决策建模的必要性。其次,由于这种方法是基于分配平衡的真实度量,因此它提供了一种评估给定数据集的给定权重的平衡的方法。最后,提出的方法在计算上是有效的,并且在轻度条件下具有理想的理论保证。我们在一系列模拟实验以及有关右心导管插入安全性和留置动脉导管的效果的研究中证明了这种EBW方法的有效性。

Bias in causal comparisons has a direct correspondence with distributional imbalance of covariates between treatment groups. Weighting strategies such as inverse propensity score weighting attempt to mitigate bias by either modeling the treatment assignment mechanism or balancing specified covariate moments. This paper introduces a new weighting method, called energy balancing, which instead aims to balance weighted covariate distributions. By directly targeting distributional imbalance, the proposed weighting strategy can be flexibly utilized in a wide variety of causal analyses, including the estimation of average treatment effects and individualized treatment rules. Our energy balancing weights (EBW) approach has several advantages over existing weighting techniques. First, it offers a model-free and robust approach for obtaining covariate balance that does not require tuning parameters, obviating the need for modeling decisions of secondary nature to the scientific question at hand. Second, since this approach is based on a genuine measure of distributional balance, it provides a means for assessing the balance induced by a given set of weights for a given dataset. Finally, the proposed method is computationally efficient and has desirable theoretical guarantees under mild conditions. We demonstrate the effectiveness of this EBW approach in a suite of simulation experiments, and in studies on the safety of right heart catheterization and the effect of indwelling arterial catheters.

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