论文标题

十倍您的光子 - 一种物理上可以筛选基于蒙特卡洛剂量分布的降低基于过滤的方差的方法

Tenfold your photons -- a physically-sound approach to filtering-based variance reduction of Monte-Carlo-simulated dose distributions

论文作者

Roser, Philipp, Birkhold, Annette, Preuhs, Alexander, Kowarschik, Markus, Fahrig, Rebecca, Maier, Andreas

论文摘要

X射线剂量不断引起对介入套件的兴趣。由于通常难以可靠地监测剂量,因此需要快速计算方法。基于蒙特卡洛(MC)方法的黄金标准的主要缺点是其计算复杂性。除了降低常见方差技术外,通常还采用过滤器方法来在一小部分时间内实现结论性结果。受这些方法的启发,我们提出了一种新颖的方法。我们根据质量的比例下对目标体积进行采样,模拟成像情况,然后恢复下采样。为此,剂量是通过质量吸收的加权,并使用带导滤波器进行了更采样和分布。最终,加权倒置,导致准确的高分辨率分布。由于需要较少的光子和边界检查,因此该方法有可能大大加速MC模拟。首先实验证实了这些假设。我们使用所提出的方法的中位数为96.7%至97.4%的剂量估计,下采样系数分别为8和4。在保持高精度的同时,该方法提供了十倍的加速。总体发现表明,该方法有可能允许进一步效率的结论。

X-ray dose constantly gains interest in the interventional suite. With dose being generally difficult to monitor reliably, fast computational methods are desirable. A major drawback of the gold standard based on Monte Carlo (MC) methods is its computational complexity. Besides common variance reduction techniques, filter approaches are often applied to achieve conclusive results within a fraction of time. Inspired by these methods, we propose a novel approach. We down-sample the target volume based on the fraction of mass, simulate the imaging situation, and then revert the down-sampling. To this end, the dose is weighted by the mass energy absorption, up-sampled, and distributed using a guided filter. Eventually, the weighting is inverted resulting in accurate high resolution dose distributions. The approach has the potential to considerably speed-up MC simulations since less photons and boundary checks are necessary. First experiments substantiate these assumptions. We achieve a median accuracy of 96.7 % to 97.4 % of the dose estimation with the proposed method and a down-sampling factor of 8 and 4, respectively. While maintaining a high accuracy, the proposed method provides for a tenfold speed-up. The overall findings suggest the conclusion that the proposed method has the potential to allow for further efficiency.

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