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By adding users as a new dimension to connectivity, on-body Internet-of-Things (IoT) devices have gained considerable momentum in recent years, while raising serious privacy and safety issues. Existing approaches to authenticate these devices limit themselves to dedicated sensors or specified user motions, undermining their widespread acceptance. This paper overcomes these limitations with a general authentication solution by integrating wireless physical layer (PHY) signatures with upper-layer protocols. The key enabling techniques are constructing representative radio propagation profiles from received signals, and developing an adversarial multi-player neural network to accurately recognize underlying radio propagation patterns and facilitate on-body device authentication. Once hearing a suspicious transmission, our system triggers a PHY-based challenge-response protocol to defend in depth against active attacks. We prove that at equilibrium, our adversarial model can extract all information about propagation patterns and eliminate any irrelevant information caused by motion variances and environment changes. We build a prototype of our system using Universal Software Radio Peripheral (USRP) devices and conduct extensive experiments with various static and dynamic body motions in typical indoor and outdoor environments. The experimental results show that our system achieves an average authentication accuracy of 91.6%, with a high area under the receiver operating characteristic curve (AUROC) of 0.96 and a better generalization performance compared with the conventional non-adversarial approach.