论文标题
基于放松模拟的半串联丝溶液的微流变学
Microrheology of semiflexible filament solutions based on relaxation simulations
论文作者
论文摘要
我们提出了一种有效的计算方法，可以获得半辅助细丝的稀释溶液的粘弹性响应。通过考虑一种基于波动隔离理论的方法，我们能够评估从弛豫模拟中浸入具有相对较低计算成本和较高精度的探针颗粒的动力学特性，与基于随机动力学相比。我们使用微流变学方法来获得复杂的剪切模量和溶液的复杂粘度通过其合规性，该溶液的依从性直接从探针粒子的动力学特性中获得，该探针粒子附着在介质模型所描述的有效培养基上，即有效的细丝模型（EFM）。应用弛豫模拟来评估弯曲能对半融合丝溶液粘弹性的影响，我们的方法可以通过将数值结果与DNA和胶原蛋白溶液的实验数据进行比较来验证。
We present an efficient computational methodology to obtain the viscoelastic response of dilute solutions of semiflexible filaments. By considering an approach based on the fluctuation-dissipation theorem, we were able to evaluate the dynamical properties of probe particles immersed in solutions of semiflexible filaments from relaxation simulations with a relatively low computational cost and higher precision in comparison to those based on stochastic dynamics. We used a microrheological approach to obtain the complex shear modulus and the complex viscosity of the solution through its compliance which was obtained directly from the dynamical properties of a probe particle attached to an effective medium described by a mesoscopic model, i.e., an effective filament model (EFM). The relaxation simulations were applied to assess the effects of the bending energy on the viscoelasticity of semiflexible filament solutions and our methodology was validated by comparing the numerical results to experimental data on DNA and collagen solutions.
