论文标题

用量子光检测和跟踪细菌

Detecting and tracking bacteria with quantum light

论文作者

Spedalieri, Gaetana, Piersimoni, Lolita, Laurino, Omar, Braunstein, Samuel L., Pirandola, Stefano

论文摘要

量子传感的领域旨在通过诉诸于光和量子检测策略的量子来源来改善在物理系统中编码的经典参数的检测和估计。可以使用相同的方法来改善生物系统上执行的当前经典测量。在这里,我们考虑了在Luria bertani肉汤中生长的两种细菌(大肠杆菌和沙门氏菌)的情况,并通过经典的分光光度计监测。它们的浓度可能与啤酒 - 蓝晶法律定律有关,并且可以通过Gompertz函数来描述它们的生长曲线。从实验数据点开始,我们推断了两种细菌的​​生长曲线,并研究了通过量子设置将实现的理论性能。特别是,我们讨论了如何通过减少光子较少数量级的样品来辐射样品,从而确定量子光的明显优势,从而在生长的早期阶段识别出明显的优势,从而讨论了细菌的生长。然后,我们在两个基本任务中显示了量子资源的优越性和限制:(i)早期发现细菌生长以及(ii)两种细菌物种之间的早期歧视。

The field of quantum sensing aims at improving the detection and estimation of classical parameters that are encoded in physical systems by resorting to quantum sources of light and quantum detection strategies. The same approach can be used to improve the current classical measurements that are performed on biological systems. Here we consider the scenario of two bacteria (E. coli and Salmonella) growing in a Luria Bertani broth and monitored by classical spectrophotometers. Their concentration can be related to the optical transmissivity via the Beer-Lambert-Bouguer's law and their growth curves can be described by means of Gompertz functions. Starting from experimental data points, we extrapolate the growth curves of the two bacteria and we study the theoretical performance that would be achieved with a quantum setup. In particular, we discuss how the bacterial growth can, in principle, be tracked by irradiating the samples with orders of magnitude fewer photons, identifying the clear superiority of quantum light in the early stages of growth. We then show the superiority and the limits of quantum resources in two basic tasks: (i) the early detection of bacterial growth and (ii) the early discrimination between two bacteria species.

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