论文标题
扩散反应流行病学模型的自适应网状细化和粗化
Adaptive Mesh Refinement and Coarsening for Diffusion-Reaction Epidemiological Models
论文作者
论文摘要
Covid-19在2020年的爆发导致人们对传染病的数学建模的兴趣激增。疾病传播可以建模为隔室模型,其中所研究的人群分为隔室,并假设从一个隔室到另一个隔室的传递率和时间率。通常,它们及时由普通微分方程(ODE)的系统组成。一类此类模型考虑了SEIRD模型的易感,暴露,感染,恢复和已故人群。但是,这些模型并不总是说明个人从一个地区到另一个地区的运动。在这项工作中,我们将SEIRD隔室模型的配方扩展到部分微分方程的扩散反应系统,以捕获Covid-19的连续时空动力学。由于病毒的差异不仅是通过扩散来的,因此我们将源术语引入方程式系统,代表了从旅行回来的暴露的人。我们还增加了各向异性非均匀扩散的可能性。我们在\ texttt {libmesh}中实现了整个模型,这是一个开放的有限元库,它为自适应网格的细化和粗化提供了多个物理学的框架。因此,该模型可以代表几个空间量表,从而使分辨率适应疾病动力学。我们使用标准SEIRD模型来验证我们的模型,并显示了几个示例,突出了当前模型的新功能。
The outbreak of COVID-19 in 2020 has led to a surge in the interest in the mathematical modeling of infectious diseases. Disease transmission may be modeled as compartmental models, in which the population under study is divided into compartments and has assumptions about the nature and time rate of transfer from one compartment to another. Usually, they are composed of a system of ordinary differential equations (ODE's) in time. A class of such models considers the Susceptible, Exposed, Infected, Recovered, and Deceased populations, the SEIRD model. However, these models do not always account for the movement of individuals from one region to another. In this work, we extend the formulation of SEIRD compartmental models to diffusion-reaction systems of partial differential equations to capture the continuous spatio-temporal dynamics of COVID-19. Since the virus spread is not only through diffusion, we introduce a source term to the equation system, representing exposed people who return from travel. We also add the possibility of anisotropic non-homogeneous diffusion. We implement the whole model in \texttt{libMesh}, an open finite element library that provides a framework for multiphysics, considering adaptive mesh refinement and coarsening. Therefore, the model can represent several spatial scales, adapting the resolution to the disease dynamics. We verify our model with standard SEIRD models and show several examples highlighting the present model's new capabilities.