论文标题

使用胸部CT特征从各种肺部异常出发的Covid-19自动分类

Automated triage of COVID-19 from various lung abnormalities using chest CT features

论文作者

Amran, Dor, Frid-Adar, Maayan, Sagie, Nimrod, Nassar, Jannette, Kabakovitch, Asher, Greenspan, Hayit

论文摘要

Covid-19的爆发导致全球努力减速流行蔓延。为此,利用了基于胸部计算的训练(CT)筛查和对Covid-19的可疑患者的诊断,可以用作逆转录 - 转录 - 聚合酶链反应(RT-PCR)测试的支持或替代。在本文中,我们提出了一个完全自动化的基于AI的系统,该系统将输入胸部CT扫描和Triages Covid-19 Case。更具体地说,我们产生了多种描述性特征,包括肺部和感染统计,纹理,形状和位置,以训练基于机器学习的分类器,该分类器区分了COVID-19和其他肺部异常(包括社区获得的肺炎)。我们在2191个CT病例的数据集上评估了我们的系统,并在85.4%的特异性(94.0%的ROC-AUC)的敏感性下证明了稳健的解决方案,其灵敏度为90.8%。此外,我们还提供了一项精心设计的特征分析和消融研究,以探讨每个功能的重要性。

The outbreak of COVID-19 has lead to a global effort to decelerate the pandemic spread. For this purpose chest computed-tomography (CT) based screening and diagnosis of COVID-19 suspected patients is utilized, either as a support or replacement to reverse transcription-polymerase chain reaction (RT-PCR) test. In this paper, we propose a fully automated AI based system that takes as input chest CT scans and triages COVID-19 cases. More specifically, we produce multiple descriptive features, including lung and infections statistics, texture, shape and location, to train a machine learning based classifier that distinguishes between COVID-19 and other lung abnormalities (including community acquired pneumonia). We evaluated our system on a dataset of 2191 CT cases and demonstrated a robust solution with 90.8% sensitivity at 85.4% specificity with 94.0% ROC-AUC. In addition, we present an elaborated feature analysis and ablation study to explore the importance of each feature.

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