论文标题

估计希腊雅典大都会地区第一次流行病期间SARS-COV-2感染的有效繁殖数

Estimation of the effective reproduction number for SARS-CoV-2 infection during the first epidemic wave in the metropolitan area of Athens, Greece

论文作者

Kaloudis, Konstantinos, Kevrekidis, George A., Maltezou, Helena C., Anastassopoulou, Cleo, Tsakris, Athanasios, Russo, Lucia

论文摘要

在此,我们提供了有关在大流行的第一波(2020年2月26日至2月15日)期间,在希腊雅典大都市地区的有效繁殖数$ r_e $的估计。为了进行计算,我们以一种比较方法实现了$ r_e $的两种最广泛使用的方法,该方法是Wallinga和Teunis以及Cori等人的。从希腊的SARS-COV-2感染国家数据库中检索了数据。我们的分析表明,在3月15日暂停全国各个级别的教育机构运营后不久,RE的预期价值在3月10日暂停后不久,以及所有零售活动的关闭(CAFES,酒吧,酒吧,博物馆,购物中心,体育设施和餐厅)于3月13日逐渐置于$ niffection $ niver的日期。在此期间,由于通知案件数量有限而导致的高度不确定性。最后,我们讨论用于估计$ r_e $的方法的局限性和陷阱,强调了这种分析的结果应仅由政策制定者视为指示。

Herein, we provide estimations for the effective reproduction number $R_e$ for the greater metropolitan area of Athens, Greece during the first wave of the pandemic (February 26-May 15, 2020). For our calculations, we implemented, in a comparative approach, the two most widely used methods for the estimation of $R_e$, that by Wallinga and Teunis and by Cori et al. Data were retrieved from the national database of SARS-CoV-2 infections in Greece. Our analysis revealed that the expected value of Re dropped below 1 around March 15, shortly after the suspension of the operation of educational institutions of all levels nationwide on March 10, and the closing of all retail activities (cafes, bars, museums, shopping centres, sports facilities and restaurants) on March 13. On May 4, the date on which the gradual relaxation of the strict lockdown commenced, the expected value of $R_e$ was slightly below 1, however with relatively high levels of uncertainty due to the limited number of notified cases during this period. Finally, we discuss the limitations and pitfalls of the methods utilized for the estimation of the $R_e$, highlighting that the results of such analyses should be considered only as indicative by policy makers.

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