论文标题
冷气血浆使用氦气,氩气和氮作为癌症治疗的喂养气体激活去离子水
Cold atmospheric plasma activated deionized water using helium, argon, and nitrogen as feeding gas for cancer therapy
论文作者
论文摘要
血浆活化培养基,含有活性氧(ROS)和反应性氮种(RNS),已被用作癌症治疗,用作间接治疗方法。在这里,我们报告了使用氦(HE),Argon(AR)和氮(N2)作为癌症治疗的喂食气体(N2)的冷大气等离子体(CAP)激活的去离子(DI)水。诊断出具有不同喂养气体的CAP激活DI水的基本特征,并还记录了三种溶液对乳腺癌细胞和胃癌细胞的影响。我们的发现表明,用CAP用He喂养气体处理的DI水对预培养的乳腺癌细胞和胃癌细胞的凋亡有更强的作用。这些结果归因于使用He作为喂食气体在帽激活的DI水中产生的ROS浓度较高。
Plasma activated medium, containing reactive oxygen species (ROS) and reactive nitrogen species (RNS), has been used for cancer treatment as an indirect treatment method. Here we report cold atmospheric plasma (CAP) activated deionized (DI) water using helium (He), argon (Ar), and nitrogen (N2) as feeding gas for the cancer therapy. Basic characteristics of CAP activated DI water with different feeding gases were diagnosed and the effects of three solutions on the breast cancer cells and gastric cancer cells were also recorded. Our findings show that DI water treated by CAP with He feeding gas has a much stronger effect on apoptosis in precultured breast cancer cells and gastric cancer cells. These results are attributed to the higher concentration of ROS generated in CAP-activated DI water using He as feeding gas.