论文标题
关于块 - 平行布尔网络:位置纸
About block-parallel Boolean networks: a position paper
论文作者
论文摘要
在自动机网络中,众所周知,随着时间的推移,实体更新其状态的方式对其动态产生了重大影响。特别是,根据所选的更新时间表,潜在的动力学系统可能表现出或多或少的渐近动力学行为,例如固定点或限制周期。由于这种数学模型已用于生物网络建模的框架中,因此很快就会出现选择适当的更新时间表的问题。在本说明中,专注于布尔网络,我们的目的是强调,随着时间的推移,适当的思考法规和遗传表达的方式当然不是考虑从异步性隔离同步性的墙壁,因为它们实际上相得益彰。特别是,我们强调了特定的更新时间表,即块 - 平行更新时间表,从理论的角度来看,其内在特征仍然不知道,在生物建模的背景下,承认现实且相关的属性,并且当然值得从社区引起更多关注。
In automata networks, it is well known that the way entities update their states over time has a major impact on their dynamics. In particular, depending on the chosen update schedule, the underlying dynamical systems may exhibit more or less asymptotic dynamical behaviours such as fixed points or limit cycles. Since such mathematical models have been used in the framework of biological networks modelling, the question of choosing appropriate update schedules has arised soon. In this note, focusing on Boolean networks, our aim is to emphasise that the adequate way of thinking regulations and genetic expression over time is certainly not to consider a wall segregating synchronicity from asynchronicity because they actually complement rather well. In particular, we highlight that specific update schedules, namely block-parallel update schedules, whose intrinsic features are still not known from a theoretical point of view, admit realistic and pertinent properties in the context of biological modelling and deserve certainly more attention from the community.