论文标题
通过从Cine MR图像传播轮廓的Gadolinium晚期增强MR图像的心肌分割
Myocardial Segmentation of Late Gadolinium Enhanced MR Images by Propagation of Contours from Cine MR Images
论文作者
论文摘要
由于梗塞区域中对比剂的积累而导致的强度异质性，gadolinium疗法增强（LGE）心脏MR（CMR）图像的自动分割通常很困难。在本文中，我们提出了一个自动分割框架，该框架在同一患者的相应的Cine和LGE图像之间充分利用共享信息。鉴于Cine CMR图像中的心肌轮廓，所提出的框架以粗到精细的方式准确地分割了LGE CMR图像。首先在相应的Cine和LGE图像对之间执行仿射登记，然后进行非辅助注册，最后是由源自LGE图像的局部特征驱动的心肌轮廓的局部变形。具有专家概述地面真相的真实患者数据的实验结果表明，该框架可以为LGE CMR图像的心肌分割产生准确可靠的结果。
Automatic segmentation of myocardium in Late Gadolinium Enhanced (LGE) Cardiac MR (CMR) images is often difficult due to the intensity heterogeneity resulting from accumulation of contrast agent in infarcted areas. In this paper, we propose an automatic segmentation framework that fully utilizes shared information between corresponding cine and LGE images of a same patient. Given myocardial contours in cine CMR images, the proposed framework achieves accurate segmentation of LGE CMR images in a coarse-to-fine manner. Affine registration is first performed between the corresponding cine and LGE image pair, followed by nonrigid registration, and finally local deformation of myocardial contours driven by forces derived from local features of the LGE image. Experimental results on real patient data with expert outlined ground truth show that the proposed framework can generate accurate and reliable results for myocardial segmentation of LGE CMR images.
