论文标题

自发曲率效应以外的异质膜中的蛋白 - 脂质结构域

Protein-lipid domains in heterogeneous membranes beyond spontaneous curvature effects

论文作者

Nowakowski, Piotr, Stumpf, Bernd Henning, Smith, Ana-Sunčana, Maciołek, Anna

论文摘要

我们研究了由两个阶参数描述的脂质双层膜的模型:使用高斯模型描述的化学成分以及用有限厚度或等效的膜的弹性变形模型所描述的空间构型,用于粘附的膜。我们假设并从物理上解释两个阶参数之间的线性耦合。使用精确解决方案,我们计算相关函数和顺序参数概要文件。我们还研究围绕膜上夹杂物形成的域。我们提出并比较六种不同的方法来量化此类域的大小。尽管它具有简单性,但该模型具有许多有趣的功能,例如Fisher-Widom系列或两个不同的关键区域。

We study a model of a lipid bilayer membrane described by two order parameters: the chemical composition described using the Gaussian model and the spatial configuration described with the elastic deformation model of a membrane with a finite thickness, or equivalently, for an adherent membrane. We assume and explain on physical grounds the linear coupling between the two order parameters. Using the exact solution, we calculate the correlation functions and order parameters profiles. We also study the domains that form around inclusions on the membrane. We propose and compare six distinct ways to quantify the size of such domains. Despite of its simplicity, the model has many interesting features like Fisher-Widom line or two distinct critical regions.

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