学术文献库

Abdominal Aortic Aneurysm (AAA) is an enlargement in the lower part of the main artery Aorta by 1.5 times its normal diameter. AAA can cause death if rupture occurs. Elective surgeries are recommended to prevent rupture based on geometrical measurements of AAA diameter and diameter growth rate. Reliability of these geometric parameters to predict the AAA rupture risk has been questioned, and biomechanical assessment has been proposed to distinguish between patients with high and low risk of rupture. Stress in aneurysm wall is the main variable of interest in such assessment. Most studies use finite element method to compute AAA stress. This requires discretising patient-specific geometry (aneurysm wall and intraluminal thrombus ILT) into finite elements/meshes. Tetrahedral elements are most commonly used as they can be generated in seemingly automated and effortless way. In practice, however, due to complex aneurysm geometry, the process tends to require time consuming mesh optimisation to ensure sufficiently high quality of tetrahedral elements. Furthermore, ensuring solution convergence requires large number of tetrahedral elements, which leads to long computation times. In this study, we focus on generation of hexahedral meshes as they are known to provide converged solution for smaller number of elements than tetrahedral meshes. Generation of hexahedral meshes for continua with complex/irregular geometry, such as aneurysms, requires analyst interaction. We propose a procedure for generating high quality patient-specific hexahedral discretisation of aneurysm wall using the algorithms available in commercial software package for mesh generation. For aneurysm cases, we demonstrate that the procedure facilitates patient-specific mesh generation within timeframe consistent with clinical workflow constraints while requiring only limited input from the analyst.