论文标题

目标研究:测量差异的概念模型和框架

The Target Study: A Conceptual Model and Framework for Measuring Disparity

论文作者

Jackson, John W., Hsu, Yea-Jen, Greer, Raquel C., Boonyasai, Romsai T., Howe, Chanelle J.

论文摘要

我们提出了一个概念模型,以衡量差异 - 目标研究 - 社会群体可能在允许的协变量上相似地位于(即平衡)。我们的模型基于抽样设计,无法干预以分配社会群体成员身份或更改允许的协变量。为了解决非随机样本选择,我们将模型扩展到概括或运输差异或评估与资格相关变量的干预后,以消除了撞机分层的形式。为了避免从差异的入学时间偏见,我们通过平衡社会群体的入学时间来汇总特定时间的研究结果。为了提供模拟我们的模型的框架,我们讨论了研究设计,数据结构以及G-Compunt和加权估计器。我们将基于抽样的模型与用于医疗保健和算法公平的突出分解模型进行比较。我们为所有估计器提供R代码,并应用我们的方法来测量使用电子病历在高血压控制中的卫生系统差异。

We present a conceptual model to measure disparity--the target study--where social groups may be similarly situated (i.e., balanced) on allowable covariates. Our model, based on a sampling design, does not intervene to assign social group membership or alter allowable covariates. To address non-random sample selection, we extend our model to generalize or transport disparity or to assess disparity after an intervention on eligibility-related variables that eliminates forms of collider-stratification. To avoid bias from differential timing of enrollment, we aggregate time-specific study results by balancing calendar time of enrollment across social groups. To provide a framework for emulating our model, we discuss study designs, data structures, and G-computation and weighting estimators. We compare our sampling-based model to prominent decomposition-based models used in healthcare and algorithmic fairness. We provide R code for all estimators and apply our methods to measure health system disparities in hypertension control using electronic medical records.

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