论文标题

无回报的点:即使对于简单的突变模型,过量突变率也可能发生

The Point of No Return: Evolution of Excess Mutation Rate is Possible Even for Simple Mutation Models

论文作者

Mintz, Brian, Fu, Feng

论文摘要

储层计算是预测湍流的有力工具,其简单的架构具有处理大型系统的计算效率。然而,其实现通常需要完整的状态向量测量和系统非线性知识。我们使用非线性投影函数将系统测量扩展到高维空间,然后将其输入到储层中以获得预测。我们展示了这种储层计算网络在时空混沌系统上的应用,该系统模拟了湍流的若干特征。我们表明,使用径向基函数作为非线性投影器,即使只有部分观测并且不知道控制方程,也能稳健地捕捉复杂的系统非线性。最后,我们表明,当测量稀疏、不完整且带有噪声,甚至控制方程变得不准确时,我们的网络仍然可以产生相当准确的预测,从而为实际湍流系统的无模型预测铺平了道路。

Under constant selection, each trait has a fixed fitness, and small mutation rates allow populations to efficiently exploit the optimal trait. Therefore it is reasonable to expect mutation rates will evolve downwards. However, we find this need not be the case, examining several models of mutation. While upwards evolution of mutation rate has been found with frequency or time dependent fitness, we demonstrate its possibility in a much simpler context. This work uses adaptive dynamics to study the evolution of mutation rate, and the replicator-mutator equation to model trait evolution. Our approach differs from previous studies by considering a wide variety of methods to represent mutation. We use a finite string approach inspired by genetics, as well as a model of local mutation on a discretization of the unit intervals, handling mutation beyond the endpoints in three ways. The main contribution of this work is a demonstration that the evolution of mutation rate can be significantly more complicated than what is usually expected in relatively simple models.

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