论文标题

单切大腿CT肌肉组分割,域适应性和自我训练

Single Slice Thigh CT Muscle Group Segmentation with Domain Adaptation and Self-Training

论文作者

Yang, Qi, Yu, Xin, Lee, Ho Hin, Cai, Leon Y., Xu, Kaiwen, Bao, Shunxing, Huo, Yuankai, Moore, Ann Zenobia, Makrogiannis, Sokratis, Ferrucci, Luigi, Landman, Bennett A.

论文摘要

目的:大腿肌肉组分割对于评估肌肉解剖学,代谢疾病和衰老很重要。用磁共振(MR)成像量化肌肉组织的许多努力,包括单个肌肉的手动注释。但是,利用MR图像中的公开注释以实现单片计算机断层扫描(CT)大腿图像上的肌肉群体分割是具有挑战性的。 方法:我们提出了一个无监督的域适应管道,并自训练将标签从3D MR转移到单个CT切片。首先,我们将图像外观从MR转换为使用Cyclean,并同时将合成的CT图像馈送到分段器。根据分段者推断的伪标签的熵,将单个CT切片分为硬且容易的人群。在基于解剖学假设的易于群的pseudo标签之后,应用了轻松而硬拆分的自我训练来微调细分器。 结果:在152张扣留单个CT大腿图像上,提议的管道在所有肌肉群中的平均骰子达到了0.888(0.041),包括萨托里乌斯,腿筋,骨髓肌股股骨和gracilis。肌肉 结论:据我们所知,这是第一个实现从MR到CT适应大腿成像域的管道。拟议的管道在2D单切CT大腿图像上提取肌肉组有效且健壮。该容器可在https://github.com/masilab/masilab/da_ct_muscle_seg上公开使用。

Objective: Thigh muscle group segmentation is important for assessment of muscle anatomy, metabolic disease and aging. Many efforts have been put into quantifying muscle tissues with magnetic resonance (MR) imaging including manual annotation of individual muscles. However, leveraging publicly available annotations in MR images to achieve muscle group segmentation on single slice computed tomography (CT) thigh images is challenging. Method: We propose an unsupervised domain adaptation pipeline with self-training to transfer labels from 3D MR to single CT slice. First, we transform the image appearance from MR to CT with CycleGAN and feed the synthesized CT images to a segmenter simultaneously. Single CT slices are divided into hard and easy cohorts based on the entropy of pseudo labels inferenced by the segmenter. After refining easy cohort pseudo labels based on anatomical assumption, self-training with easy and hard splits is applied to fine tune the segmenter. Results: On 152 withheld single CT thigh images, the proposed pipeline achieved a mean Dice of 0.888(0.041) across all muscle groups including sartorius, hamstrings, quadriceps femoris and gracilis. muscles Conclusion: To our best knowledge, this is the first pipeline to achieve thigh imaging domain adaptation from MR to CT. The proposed pipeline is effective and robust in extracting muscle groups on 2D single slice CT thigh images.The container is available for public use at https://github.com/MASILab/DA_CT_muscle_seg

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