论文标题

基于两阶段上下文的基于变压器的卷积神经网络,用于从CT图像中提取气道

Two-stage Contextual Transformer-based Convolutional Neural Network for Airway Extraction from CT Images

论文作者

Wu, Yanan, Zhao, Shuiqing, Qi, Shouliang, Feng, Jie, Pang, Haowen, Chang, Runsheng, Bai, Long, Li, Mengqi, Xia, Shuyue, Qian, Wei, Ren, Hongliang

论文摘要

从计算机断层扫描(CT)图像中提取准确的气道是计划导航支气管镜检查和气道相关慢性阻塞性肺疾病(COPD)的定量评估的关键步骤。现有的方法具有挑战性,要充分分段气道,尤其是高代气道,并具有有限标签的限制,并且无法满足COPD中的临床用途。我们建议使用CT图像进行新型的两阶段3D上下文的U-NET,用于气道分割。该方法由两个阶段组成,进行初始和精制的气道分割。两阶段模型与不同的气道掩码共享相同的子网。在子网的编码器和解码器路径中既有有效地完成高质量的气道分割,又​​在编码器和解码器路径中执行上下文变压器块。在第一阶段,将提供总气道掩码和CT图像,并在第二阶段提供肺内气道掩码和相应的CT扫描。然后将两阶段方法的预测合并为最终预测。在内部和多个公共数据集上进行了广泛的实验。定量和定性分析表明,我们提出的方法在完成最新的气道分割性能的同时提取了更多的树枝和长度。该代码可在https://github.com/zhaozsq/airway_segentation上获得。

Accurate airway extraction from computed tomography (CT) images is a critical step for planning navigation bronchoscopy and quantitative assessment of airway-related chronic obstructive pulmonary disease (COPD). The existing methods are challenging to sufficiently segment the airway, especially the high-generation airway, with the constraint of the limited label and cannot meet the clinical use in COPD. We propose a novel two-stage 3D contextual transformer-based U-Net for airway segmentation using CT images. The method consists of two stages, performing initial and refined airway segmentation. The two-stage model shares the same subnetwork with different airway masks as input. Contextual transformer block is performed both in the encoder and decoder path of the subnetwork to finish high-quality airway segmentation effectively. In the first stage, the total airway mask and CT images are provided to the subnetwork, and the intrapulmonary airway mask and corresponding CT scans to the subnetwork in the second stage. Then the predictions of the two-stage method are merged as the final prediction. Extensive experiments were performed on in-house and multiple public datasets. Quantitative and qualitative analysis demonstrate that our proposed method extracted much more branches and lengths of the tree while accomplishing state-of-the-art airway segmentation performance. The code is available at https://github.com/zhaozsq/airway_segmentation.

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